El grupo de investigación tiene como objetivo generar conocimiento en áreas relevantes para el país en temáticas relacionadas con la salud y producción animal, medicina de poblaciones, zoonosis y medicina de la conservación. Para el cumplimiento de este objetivo el grupo desarrolla proyectos de investigación enmarcado en cinco líneas de investigación las cuales son: Producción animal, Medicina de Poblaciones, Medicina de la Conservación, Zoonosis y Salud Animal. Los proyectos realizados en el campo de la medicina de la conservación han permitido la conservación de especies nativas tales como el pez capitán de la sabana y la Pacarana.


Using of Okara in diets for growing broilers

This study aimed to evaluate the effects of okara inclusion in diet for growing broilers on performance, carcass yield, blood and bone variables, quality and lipid oxidation of meat and economic viability. For that, 575 Cobb 21-days-old male broilers were distributed in a completely randomized design with four levels of okara inclusion (25, 50, 75 and 100 g of okara/kg diet) and a control group with five replicates and 23 birds each. There was no difference (P>0.05) in function of okara levels on the performance variables, carcass yield, bone variables and serum triglycerides, calcium and phosphorus at 42 days old. Serum cholesterol levels showed a quadratic response (P<0.05), in which the lowest value estimated was 65.3 g of okara/kg of diet. Okara can be included in diets for broilers up to the level of 100g/kg without affecting the performance, carcass yield, bone variables and lipid oxidation of meat. However, the best economic results were observed up to 50g of okara/kg of diet.

Skull pathology in 10 cats with patellar fracture and dental anomaly syndrome

Case series summary: The aim of this case series is to describe the clinical and radiological features of mandibular and maxillary abnormalities in cats diagnosed with patellar fractures and dental anomalies, a condition that we have named ‘patellar fracture and dental anomaly syndrome’ (PADS), also known previously as ‘knees and teeth syndrome’. Where available, clinical records, skull and/or intraoral dental radiographs, head CT images, microbiology and histopathology reports were collected, and follow-up was obtained. Ten cats with mandibular or maxillary abnormalities were identified. Common clinical features included multiple persistent deciduous teeth, gingivitis and swellings of the jaw. Skull radiographs were available for 7/10 cats and head CT images were available for one cat. Findings included marked bony and periosteal proliferation, hypodontia, root resorption, root malformation and unerupted permanent teeth. Where available, microbiology and histopathology results were consistent with osteomyelitis. Relevance and novel information: Mandibular and maxillary abnormalities are an additional unreported clinical feature of the rare condition that we have termed PADS. Radiologically, these lesions can have an aggressive appearance, which can mimic neoplasia. Medical management with antibiotic and anti-inflammatory therapy improves clinical signs in the short term; however, surgical extraction of persistent deciduous and unerupted permanent teeth, and debridement of proliferative and necrotic bone appear to be necessary for an improved outcome. Additional information on long-term outcome is required. © The Author(s) 2018.

Resposta de linfonodos em bovinos inoculados a campo com a vacina recombinante rSBm7462 anti Rhipicephalus (Boophilus) microplus)

A dependência exclusiva de compostos químicos para o controle de Rhipicephalus (Boophilus) microplus tornou-se uma das maiores preocupações científicas e econômicas dos últimos anos, e como consequência, estão sendo realizadas pesquisas para o desenvolvimento de vacinas. O objetivo deste trabalho foi avaliar a resposta de linfonodos de bovinos imunizados a campo com o peptídeo rSBm7462 anti R. (B.) microplus. Foram utilizados 14 bovinos mestiços (Bos taurus x Bos indicus), com idades entre 4-10 meses, mantidos em duas propriedades rurais do norte do estado de Minas Gerais. Os animais receberam três imunizações do peptídeo rSBm7462, aplicados por via subcutânea, com intervalo de 30 dias. Após 15 dias de cada imunização, os linfonodos pré-escapulares foram coletados e fixados por 18 horas em formol. Posteriormente, foram incluídos em Paraplast e as amostras foram coradas pela técnica hematoxilina-eosina (HE) para a observação de eventos celulares. Para a identificação do antígeno nos linfonodos dos animais imunizados, foi realizada a técnica de imuno-histoquímica (IHQ) com o método peroxidase-anti-peroxidase (PAP). A resposta de linfonodos dos bovinos inoculados foi avaliada pelas análises de formação de centros germinais (CG), hiperplasia de cordões medulares (CM) e a presença do antígeno rSBm7462 em células PAP+, demonstrando que o peptídeo recombinante rSBm7462 induz uma resposta imune adaptativa T-dependente, caracterizada nos tecidos linfóides secundários pela formação de estruturas que conferem afinidade e memória imunológica.

Propolis residue inclusion in the diet affects digestive enzyme activity in broiler chickens

This study investigated the effects of the inclusion of solid propolis residue (PR) from alcoholic propolis extraction in the diets of broiler chickens from 1 to 21-d of age on their performance, intestinal morphology, and digestive enzyme activity. 405 male chicks were distributed in a completely randomized design with five treatments (inclusion of 0, 1, 2, 3 and 4% PR in the diets), and three replications with 27 birds each. The birds were fed experimental diets from 1 to 21-d of age and basal diet from 22 to 42-d of age. Feed intake (from 1 to 21-d and 1 to 42-d of age) decreased linearly with increasing levels of PR inclusion (P < 0.05). Dietary inclusion of PR did not affect intestinal morphology at 7 and 21-d of age (P > 0.05). Pancreatic amylase activity presented a quadratic response at 7 and 21-d of age, with its lowest activity estimated at 2.45 and 1.91% PR inclusion, respectively. At 7-d of age, trypsin activity decreased linearly, whereas chymotrypsin activity varied quadratically, with its activity estimated at 2.06% PR inclusion. Intestinal maltase activity varied quadratically with lowest activity predicted at 1.57% PR inclusion at 21-d of age. The dietary inclusion of solid propolis residue of propolis decreases feed intake in broilers and modulates their intestinal and pancreatic enzyme activity.

Population structure and genetic diversity in ColombianSimmental cattle

A vital requirement to design and implement a breeding program is to know the structure and genetic diversity of a population.The aim of this study was to characterize population structure and genetic diversity of the Colombian Simmental cattle. Thepedigree file included 27,985 animals born from 1975 to 2017. The level of genetic diversity and breed structure was evaluatedthrough probabilities of gene origin expressed via effective number of founders, ancestors and founders genomes. The inbreedingrates and the degree of genetic connectivity were estimated using a regression analysis and a genetic drift variance analysis,respectively. The lowest effective number of founders and ancestors were 50 and 38 by year, respectively. The average inbreedingby year of birth decreased from 5.06% in 1980 to 2.25% in 2017. The dairy line genetic contributions in the overall populationincreased significantly in the last 37 years, and the beef line contribution decreased. Regarding the genetic connectivity,Colombian regions (administrative divisions) with the largest cattle population had higher values. The results indicate that theavailability of European and North American bulls contributes to genetic diversity by increasing the effective number of foundersover time in the Colombian Simmental cattle population. However, the intensive use of relatively few founders causes anunbalanced genetic contribution and the loss of genetic diversity by gene pool erosion.