Synthesis of new 1,2-diaryl[2]benzopyrano[3,4-d]imidazol-5(1H)-one derivatives mediated by ceric ammonium nitrate
Fecha de publicación: 12/07/2017

In summary, we have implemented a simple two-step methodology for obtaining a new series of 1,2-diaryl[2]benzopyrano[3,4-d]imidazol-5(1H)-one derivatives 6a–j in acceptable to good yields through a carbon-nitrogen bond-forming reaction by using CAN as key mediator. Which constitutes a simple way to form this interesting tricyclic system that fused isocoumarin and imidazole rings, what is of interest to develop new bioactive derivatives. The role of the CAN is important since it acts as Lewis catalyst, as it was proposed in the mechanism.