Químico Universidad Nacional de Colombia con maestría en química de la misma universidad. Línea principal de trabajo en síntesis orgánica heterocíclica. Experiencia docente universitaria desde 2011, vinculado con la universidad de Ciencias Aplicadas y Ambientales desde 2012.
LINEAS DE TRABAJO: Síntesis de Compuestos Heterocíclicos
PRODUCTOS DESTACADOS
Synthesis of new 1,2-diaryl[2]benzopyrano[3,4-d]imidazol-5(1H)-one derivatives mediated by ceric ammonium nitrate
Fecha de publicación: 12/07/2017
In summary, we have implemented a simple two-step methodology for obtaining a new series of 1,2-diaryl[2]benzopyrano[3,4-d]imidazol-5(1H)-one derivatives 6a–j in acceptable to good yields through a carbon-nitrogen bond-forming reaction by using CAN as key mediator. Which constitutes a simple way to form this interesting tricyclic system that fused isocoumarin and imidazole rings, what is of interest to develop new bioactive derivatives. The role of the CAN is important since it acts as Lewis catalyst, as it was proposed in the mechanism.
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