Catalina Esther Avendaño Valenzuela

 cavendano@udca.edu.co

GRUPOS DE INVESTIGACIÓN: CIENCIA ANIMAL

LÍNEAS DE INVESTIGACIÓN:   Salud Animal – Enfermedades Infecciosas Salud Animal – Vacunas

FACULTAD:  Ciencias Agropecuarias

CATEGORÍA COLCIENCIAS:    

NIVEL DE FORMACIÓN: Doctorado

Profesional de Microbiología Agrícola y Veterinaria, con especialización en Sanidad Animal y Doctor por la Universidad de Zaragoza en Medicina y Sanidad Animal. Con experiencia y habilidades en la docencia de microbiología, inmunología y diagnóstico en el laboratorio clínico; y con experiencia en investigación de parasitología, inmunología y biología molecular. Con capacidades para el manejo de grupos, trabajo interprofesional en equipo a nivel nacional e internacional. En el área de extensión y divulgación con capacidades para estructurar y presentar conferencias de carácter técnico y científico en las áreas mencionadas. Con dominio de lectura, escritura e interpretación de información científica en inglés.

PRODUCTOS DESTACADOS

Molecular characterization of Cryptosporidium parvum and Cryptosporidium hominis GP60 subtypes worldwide
Fecha de publicación: 01/09/2017

Cryptosporidium is a zoonotic parasite very important in animal health as well as in public health. It is because this is one of the main causes of diarrhea in children, calves, lambs and other variety of youth mammalians in a lot of countries. The globalization has enabled the exchange of biological material in different regions worldwide, encouraging the spread of diseases and exposure to these biological agents to different environmental conditions, inducing adaptation through genetic changes. Based in the polymorphism of the gene for GP60, this review intended to present the distribution of Cryptosporidium parvum and Cryptosporidium hominis in humans and calves worldwide. The subtype that affects cattle more frequently corresponds to IIaA15G2R; while the subtype most frequently isolated from human samples is IaA19G2.


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Genetic uniqueness of Cryptosporidium parvum from dairy calves in Colombia
Fecha de publicación: 26/02/2018

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Cryptosporidium spp. CP15 and CSL protein-derived synthetic peptides’ immunogenicity and in vitro seroneutralisation capability
Fecha de publicación: 29/10/2018

Cryptosporidium spp. is a zoonotic intracellular protozoan and a significant cause of diarrhoea in humans and animals worldwide. This parasite can cause high morbidity in immunocompromised people and children in developing countries, livestock being the main reservoir. This study was aimed at performing preliminary tests on Swiss albino weaned mice (ICR) to evaluate the humoral immune response induced against peptides derived from Cryptosporidium parvum CP15 (15 kDa sporozoite surface antigen) and CSL (circumsporozoite-like antigen) proteins. Peptides were identified and characterised using bioinformatics tools and were chemically synthesised. The antibody response was determined and the neutralising effect of antibodies was measured in cell culture. Despite all peptides studied here were capable of stimulating antibody production, neutralising antibodies were detected for just two of the CP15-derived ones. Additional studies aimed at evaluating further the potential of such peptides as vaccine candidates are thus recommended. © 2018 Elsevier Ltd


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